General Description Of Systemic Lupus Erythematosus

General Description Systemic Lupus Erythematosus, SLE, is a chronic inflammatory disease that occurs when the body’s immune system attacks its own tissue and organs. Inflammation can affect many different body systems including joints, skin, kidneys, blood cells, brain, heart, and lungs. Lupus can be difficult to diagnose because the signs and symptoms, and a physical examination lead to a diagnosis. A facial rash across both cheeks resembling wings of butterfly is the most distinctive sign of lupus that occurs in many but not all cases. There is no cure for lupus and only treatments that can help control symptoms. Pathophysiology The inflammation caused by lupus can affect many areas of the body. It can cause serious kidney damage and†¦show more content†¦The bone most commonly affected is the hip. Women with lupus have an increased risk of having a miscarriage. The risk of high blood pressure known as preeclampsia during pregnancy and preterm birth increases with lupus. Doctors recommend delaying pregnancy until the disease has been under control for at least six months to reduce these complications. Lupus results from a combination of genetics and environment. Inherited predisposition may develop the disease after contact with triggers. The cause for most cases is unknown. Potential triggers include sunlight, infections, and medications. Sun exposure may bring on lupus skin lesions or trigger an internal response. An infection can initiate lupus or cause a relapse in some people. Certain types of anti-seizure medications, blood pressure medications and antibiotics can trigger lupus. The symptoms o f those with drug-induced lupus will go away once they stop taking the medication. Lupus is more common in women, African-Americans, Hispanics, and Asians and most often diagnosed between the ages of 15 and 40. Symptoms Blood and urine tests combined with signs and symptoms and a physical examination lead to a diagnosis. The most distinctive sign of lupus that occurs in many but not all cases is a facial rash across both cheeks resembling the wings of a butterfly. The most common signs and symptoms include: fatigue and fever,Show MoreRelatedPodiatry Rhuematoid Arthritis8124 Words   |  33 Pagesdiagnosis techniques, pharmacological management, physical therapeutics and surgical treatment interventions. I shall explore the expected prognosis and the key developments we can expect in the future. Aetiology and Prevalence RA is a chronic, systemic and inflammatory disease that progressively impacts peripheral joints (Panayi 2011).The damage that occurs is predominantly symmetrical and polyarthropathic (Rindfleisch Muller 2005). It affects the host’s joint synovial membranes, tendon sheathsRead MoreHesi Practice31088 Words   |  125 Pagesshortness of breath. Physical findings include bilateral crackles, a third heart sound (S3), distended neck veins, elevated blood pressure, and pitting edema of the ankles. The nurse documents the severity of pitting edema as +1. What is the best description of this type of edema? A. Barely detectable depression when the thumb is released from the swollen area; normal foot and leg contours. B. Detectable depression of less than 5 mm when the thumb is released from the swollen area; normal foot and legRead MoreGsk Annual Report 2010135604 Words   |  543 Pagesstatements Financial statements of GlaxoSmithKline plc prepared under UK GAAP 102 103 104 109 188 Shareholder information Quarterly trend Five year record Product development pipeline Share price and dividends Nature of trading market Annual General Meeting Investor relations and Registrar Taxation information for shareholders Glossary of terms Index 192 200 203 207 208 208 208 210 211 212 Underlying sales growth excludes pandemic products, Avandia and Valtrex. See page 21. CER% represents